SAMHD1 expression modulates innate immune activation and correlates with ovarian cancer prognosis

PURPOSE: SAMHD1 is a deoxynucleotide triphosphate (dNTP) triphosphohydrolase which has been proposed as a putative prognostic factor in haematological cancers and certain solid tumours, although with controversial data. Here, we evaluate SAMHD1 function in ovarian cancer, both in vitro and in ovaria...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Chamorro, Lucía, Felip, Eudald, Bernat-Peguera, Adrià, Ezeonwumelu, Ifeanyi Jude, Teruel, Iris, Martínez-Cardús, Anna, Clotet, Bonaventura, Riveira-Muñoz, Eva, Romeo, Margarita, Margelí, Mireia, Ballana, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948397/
https://www.ncbi.nlm.nih.gov/pubmed/36845138
http://dx.doi.org/10.3389/fimmu.2023.1112761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948397/
https://www.ncbi.nlm.nih.gov/pubmed/36845138
http://dx.doi.org/10.3389/fimmu.2023.1112761

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