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The critical role of KLF4 in regulating the activation of A1/A2 reactive astrocytes following ischemic stroke

BACKGROUND: We have previously demonstrated that the expression of kruppel-like transcription factor-4 (KLF-4) is upregulated in astrocytes following acute ischemic stroke (AIS) and found that KLF4 confers vascular protection against cerebral ischemic injury. However, the functional role of KLF4 in...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Li, Longxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948409/
https://www.ncbi.nlm.nih.gov/pubmed/36823628
http://dx.doi.org/10.1186/s12974-023-02742-9