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Screening for bilayer-active and likely cytotoxic molecules reveals bilayer-mediated regulation of cell function
A perennial problem encountered when using small molecules (drugs) to manipulate cell or protein function is to assess whether observed changes in function result from specific interactions with a desired target or from less specific off-target mechanisms. This is important in laboratory research as...
Autores principales: | Peyear, Thasin A., Andersen, Olaf S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948646/ https://www.ncbi.nlm.nih.gov/pubmed/36763053 http://dx.doi.org/10.1085/jgp.202213247 |
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