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Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance

Tolerance of Mycobacterium tuberculosis to antibiotics contributes to the long duration of tuberculosis (TB) treatment and the emergence of drug-resistant strains. M. tuberculosis drug tolerance is induced by nutrient restriction, but the genetic determinants that promote antibiotic tolerance trigge...

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Detalles Bibliográficos
Autores principales: Block, Alisha M., Namugenyi, Sarah B., Palani, Nagendra P., Brokaw, Alyssa M., Zhang, Leanne, Beckman, Kenneth B., Tischler, Anna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948706/
https://www.ncbi.nlm.nih.gov/pubmed/36598240
http://dx.doi.org/10.1128/msystems.00699-22