Cargando…
Mycobacterium tuberculosis Requires the Outer Membrane Lipid Phthiocerol Dimycocerosate for Starvation-Induced Antibiotic Tolerance
Tolerance of Mycobacterium tuberculosis to antibiotics contributes to the long duration of tuberculosis (TB) treatment and the emergence of drug-resistant strains. M. tuberculosis drug tolerance is induced by nutrient restriction, but the genetic determinants that promote antibiotic tolerance trigge...
Autores principales: | Block, Alisha M., Namugenyi, Sarah B., Palani, Nagendra P., Brokaw, Alyssa M., Zhang, Leanne, Beckman, Kenneth B., Tischler, Anna D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948706/ https://www.ncbi.nlm.nih.gov/pubmed/36598240 http://dx.doi.org/10.1128/msystems.00699-22 |
Ejemplares similares
-
Mycobacterium marinum phthiocerol dimycocerosates enhance macrophage phagosomal permeabilization and membrane damage
por: Osman, Morwan M., et al.
Publicado: (2020) -
Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis
por: Gómez-Velasco, Anaximandro, et al.
Publicado: (2013) -
Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells
por: Lerner, Thomas R., et al.
Publicado: (2018) -
Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors
por: Augenstreich, Jacques, et al.
Publicado: (2020) -
Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids
por: Astarie-Dequeker, Catherine, et al.
Publicado: (2009)