CTCF mediates CD8(+) effector differentiation through dynamic redistribution and genomic reorganization

Differentiation of effector CD8(+) T cells is instructed by stably and dynamically expressed transcription regulators. Here we show that naive-to-effector differentiation was accompanied by dynamic CTCF redistribution and extensive chromatin architectural changes. Upon CD8(+) T cell activation, CTCF...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Zhu, Shaoqi, Hu, Wei, Zhao, Xin, Shan, Qiang, Peng, Weiqun, Xue, Hai-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948760/
https://www.ncbi.nlm.nih.gov/pubmed/36752796
http://dx.doi.org/10.1084/jem.20221288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948760/
https://www.ncbi.nlm.nih.gov/pubmed/36752796
http://dx.doi.org/10.1084/jem.20221288

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