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BHLHE40/41 regulate macrophage/microglia responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues

BACKGROUND: Genetic and experimental evidence strongly implicates myeloid cells in the etiology of AD and suggests that AD-associated alleles and genes may modulate disease risk by altering the transcriptional and cellular responses of macrophages (like microglia) to damage of lipid-rich tissues (li...

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Detalles Bibliográficos
Autores principales: Podlesny-Drabiniok, Anna, Novikova, Gloriia, Liu, Yiyuan, Dunst, Josefine, Temizer, Rose, Giannarelli, Chiara, Marro, Samuele, Kreslavsky, Taras, Marcora, Edoardo, Goate, Alison Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948946/
https://www.ncbi.nlm.nih.gov/pubmed/36824752
http://dx.doi.org/10.1101/2023.02.13.528372