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Maternal infection causes dysfunctional BCR signaling in male offspring due to aberrant Xist expression

Infections during pregnancy with pathogens such as helminths correlate with altered immune responses to common childhood immunizations. However, the molecular mechanisms that underlie this remain unknown. Using our murine model of maternal schistosomiasis, when immunized, males from infected mothers...

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Detalles Bibliográficos
Autores principales: Gibbs, Lisa C., Oviedo, Juan M., Ondigo, Bartholomew N., Fairfax, Keke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948949/
https://www.ncbi.nlm.nih.gov/pubmed/36824836
http://dx.doi.org/10.1101/2023.02.13.528357