Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

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Developing astroglia play important roles in regulating synaptogenesis through secreted and contact signals. Whether they regulate postnatal axon growth is unknown. By selectively isolating exosomes using size-exclusion chromatography (SEC) and employing cell-type specific exosome reporter mice, our...

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Detalles Bibliográficos
Autores principales: Jin, Shijie, Chen, Xuan, Tian, Yang, Jarvis, Rachel, Promes, Vanessa, Yang, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948960/
https://www.ncbi.nlm.nih.gov/pubmed/36824898
http://dx.doi.org/10.1101/2023.02.14.528554
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