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A kinetic dichotomy between mitochondrial and nuclear gene expression drives OXPHOS biogenesis

Oxidative phosphorylation (OXPHOS) complexes, encoded by both mitochondrial and nuclear DNA, are essential producers of cellular ATP, but how nuclear and mitochondrial gene expression steps are coordinated to achieve balanced OXPHOS biogenesis remains unresolved. Here, we present a parallel quantita...

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Detalles Bibliográficos
Autores principales: McShane, Erik, Couvillion, Mary, Ietswaart, Robert, Prakash, Gyan, Smalec, Brendan M., Soto, Iliana, Baxter-Koenigs, Autum R., Choquet, Karine, Churchman, L. Stirling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948965/
https://www.ncbi.nlm.nih.gov/pubmed/36824735
http://dx.doi.org/10.1101/2023.02.09.527880