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Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

Pathogenesis of Pseudomonas aeruginosa infections can include bacterial survival inside epithelial cells. Previously, we showed this involves multiple roles played by the type three-secretion system (T3SS), and specifically the effector ExoS. This includes ExoS-dependent inhibition of a lytic host c...

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Detalles Bibliográficos
Autores principales: Kroken, Abby R, Klein, Keith A, Mitchell, Patrick S, Nieto, Vincent, Jedel, Eric J, Evans, David J, Fleiszig, Suzanne M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948977/
https://www.ncbi.nlm.nih.gov/pubmed/36824932
http://dx.doi.org/10.1101/2023.02.13.528260