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The mitochondrial regulation of smooth muscle cell proliferation in type 2 diabetes

BACKGROUND: Type 2 diabetes (T2D) is associated with a strongly increased risk for restenosis after angioplasty driven by proliferation of vascular smooth muscle cells (VSMCs). Here, we sought to determine whether and how mitochondrial dysfunction in T2D drives VSMC proliferation with a focus on ROS...

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Detalles Bibliográficos
Autores principales: Koval, Olha M., Nguyen, Emily K., Mittauer, Dylan J., Ait-Aissa, Karima, Chinchankar, William, Qian, Lan, Madesh, Muniswamy, Dai, Dao-Fu, Grumbach, Isabella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948984/
https://www.ncbi.nlm.nih.gov/pubmed/36824758
http://dx.doi.org/10.1101/2023.02.15.528765