Clustering rare diseases within an ontology-enriched knowledge graph

OBJECTIVE: Identifying sets of rare diseases with shared aspects of etiology and pathophysiology may enable drug repurposing and/or platform based therapeutic development. Toward that aim, we utilized an integrative knowledge graph-based approach to constructing clusters of rare diseases. MATERIALS...

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Detalles Bibliográficos
Autores principales: Sanjak, Jaleal, Zhu, Qian, Mathé, Ewy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949046/
https://www.ncbi.nlm.nih.gov/pubmed/36824742
http://dx.doi.org/10.1101/2023.02.15.528673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949046/
https://www.ncbi.nlm.nih.gov/pubmed/36824742
http://dx.doi.org/10.1101/2023.02.15.528673

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