Comparative transcriptomics reveal differential gene expression in Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms

Plasmodium vivax uses Duffy binding protein (PvDBP1) to bind to the Duffy Antigen-Chemokine Receptor (DARC) to invade human erythrocytes. Individuals who lack DARC expression (Duffy-negative) are thought to be resistance to P. vivax. In recent years, P. vivax malaria is becoming more prevalent in Af...

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Detalles Bibliográficos
Autores principales: Kepple, Daniel, Ford, Colby T., Williams, Jonathan, Abagero, Beka, Li, Shaoyu, Popovici, Jean, Yewhalaw, Delenasaw, Lo, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949051/
https://www.ncbi.nlm.nih.gov/pubmed/36824754
http://dx.doi.org/10.1101/2023.02.16.528793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949051/
https://www.ncbi.nlm.nih.gov/pubmed/36824754
http://dx.doi.org/10.1101/2023.02.16.528793

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