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Comparative transcriptomics reveal differential gene expression in Plasmodium vivax geographical isolates and implications on erythrocyte invasion mechanisms
Plasmodium vivax uses Duffy binding protein (PvDBP1) to bind to the Duffy Antigen-Chemokine Receptor (DARC) to invade human erythrocytes. Individuals who lack DARC expression (Duffy-negative) are thought to be resistance to P. vivax. In recent years, P. vivax malaria is becoming more prevalent in Af...
Autores principales: | Kepple, Daniel, Ford, Colby T., Williams, Jonathan, Abagero, Beka, Li, Shaoyu, Popovici, Jean, Yewhalaw, Delenasaw, Lo, Eugenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949051/ https://www.ncbi.nlm.nih.gov/pubmed/36824754 http://dx.doi.org/10.1101/2023.02.16.528793 |
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