Cargando…

Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAF(V600E)-induced cellular senescence in human melanocytes

Melanoma arises from transformation of melanocytes in the basal layer of the epidermis where they are surrounded by keratinocytes, with which they interact through cell contact and paracrine communication. Considerable effort has been devoted to determining how the accumulation of oncogene and tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Xin, Burks, Hope E., Ren, Ziyou, Koetsier, Jennifer L., Roth-Carter, Quinn R., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949056/
https://www.ncbi.nlm.nih.gov/pubmed/36824910
http://dx.doi.org/10.1101/2023.02.16.528886