Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans

Gene regulatory divergence between species can result from cis-acting local changes to regulatory element DNA sequences or global trans-acting changes to the regulatory environment. Understanding how these mechanisms drive regulatory evolution has been limited by challenges in identifying trans-acti...

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Detalles Bibliográficos
Autores principales: Hansen, Tyler, Fong, Sarah, Capra, John A., Hodges, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949080/
https://www.ncbi.nlm.nih.gov/pubmed/36824965
http://dx.doi.org/10.1101/2023.02.14.528376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949080/
https://www.ncbi.nlm.nih.gov/pubmed/36824965
http://dx.doi.org/10.1101/2023.02.14.528376

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