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Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans
Gene regulatory divergence between species can result from cis-acting local changes to regulatory element DNA sequences or global trans-acting changes to the regulatory environment. Understanding how these mechanisms drive regulatory evolution has been limited by challenges in identifying trans-acti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949080/ https://www.ncbi.nlm.nih.gov/pubmed/36824965 http://dx.doi.org/10.1101/2023.02.14.528376 |