Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia

The dependency of cancer cells on glucose can be targeted with high-fat low-carbohydrate ketogenic diet (KD). However, hepatic ketogenesis is suppressed in IL-6 producing cancers, which prevents the utilization of this nutrient source as energy for the organism. In two IL-6 associated murine models...

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Detalles Bibliográficos
Autores principales: Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E., Kleeman, Sam O., Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R., Connell, Claire M., Lukey, Michael J., White, Eileen P., Coll, Anthony P., Venkitaraman, Ashok R., Janowitz, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949105/
https://www.ncbi.nlm.nih.gov/pubmed/36824830
http://dx.doi.org/10.1101/2023.02.17.528937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949105/
https://www.ncbi.nlm.nih.gov/pubmed/36824830
http://dx.doi.org/10.1101/2023.02.17.528937

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