Optogenetic inhibition of the caudal substantia nigra inflates behavioral responding to uncertain threat and safety

Defensive responding is adaptive when it approximates current threat, but maladaptive when it exceeds current threat. Here we asked if the substantia nigra, a region consistently implicated in reward, is necessary to show appropriate levels of defensive responding in Pavlovian fear discrimination. R...

Descripción completa

Detalles Bibliográficos
Autores principales: Wright, Kristina M, Cieslewski, Shannon, Chu, Amanda, McDannald, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949108/
https://www.ncbi.nlm.nih.gov/pubmed/36824795
http://dx.doi.org/10.1101/2023.02.18.529041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949108/
https://www.ncbi.nlm.nih.gov/pubmed/36824795
http://dx.doi.org/10.1101/2023.02.18.529041

Ejemplares similares