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Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility

Viruses interact with receptors on the cell surface to initiate and co-ordinate infection. The distribution of receptors on host cells can be a key determinant of viral tropism and host infection. Unravelling the complex nature of virus-receptor interactions is, therefore, of fundamental importance...

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Detalles Bibliográficos
Autores principales: Mills, Jake T., Minogue, Susanna C., Snowden, Joseph S., Arden, Wynter K.C., Rowlands, David J., Stonehouse, Nicola J., Wobus, Christiane E., Herod, Morgan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949111/
https://www.ncbi.nlm.nih.gov/pubmed/36824911
http://dx.doi.org/10.1101/2023.02.17.528071