The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

The mammalian innate immune system uses germline-encoded cytosolic pattern-recognition receptors (PRRs) to detect intracellular danger signals. At least six of these PRRs are known to form multiprotein complexes called inflammasomes which activate cysteine proteases known as caspases. Canonical infl...

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Detalles Bibliográficos
Autores principales: Exconde, Patrick M., Hernandez-Chavez, Claudia, Bray, Mark B., Lopez, Jan L., Srivastava, Tamanna, Egan, Marisa S., Zhang, Jenna, Shin, Sunny, Discher, Bohdana M., Taabazuing, Cornelius Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949112/
https://www.ncbi.nlm.nih.gov/pubmed/36824844
http://dx.doi.org/10.1101/2023.02.16.528859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949112/
https://www.ncbi.nlm.nih.gov/pubmed/36824844
http://dx.doi.org/10.1101/2023.02.16.528859

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