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mRNA interactions with disordered regions control protein activity

The cytoplasm is compartmentalized into different translation environments. mRNAs use their 3′UTRs to localize to distinct cytoplasmic compartments, including TIS granules (TGs). Many transcription factors, including MYC, are translated in TGs. It was shown that translation of proteins in TGs enable...

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Detalles Bibliográficos
Autores principales: Luo, Yang, Pratihar, Supriya, Horste, Ellen H., Mitschka, Sibylle, Mey, Antonia S. J. S., Al-Hashimi, Hashim M., Mayr, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949118/
https://www.ncbi.nlm.nih.gov/pubmed/36824771
http://dx.doi.org/10.1101/2023.02.18.529068