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mRNA interactions with disordered regions control protein activity
The cytoplasm is compartmentalized into different translation environments. mRNAs use their 3′UTRs to localize to distinct cytoplasmic compartments, including TIS granules (TGs). Many transcription factors, including MYC, are translated in TGs. It was shown that translation of proteins in TGs enable...
Autores principales: | Luo, Yang, Pratihar, Supriya, Horste, Ellen H., Mitschka, Sibylle, Mey, Antonia S. J. S., Al-Hashimi, Hashim M., Mayr, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949118/ https://www.ncbi.nlm.nih.gov/pubmed/36824771 http://dx.doi.org/10.1101/2023.02.18.529068 |
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