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Transcriptional read through interrupts boundary function in Drosophila

In higher eukaryotes enhancer-promoter interactions are known to be restricted by the chromatin insulators/boundaries that delimit topologically associated domains (TADs); however, there are instances in which enhancer-promoter interactions span one or more boundary elements/TADs. At present, the me...

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Detalles Bibliográficos
Autores principales: Kyrchanova, Olga, Sokolov, Vladimir, Tikhonov, Maxim, Schedl, Paul, Georgiev, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949125/
https://www.ncbi.nlm.nih.gov/pubmed/36824960
http://dx.doi.org/10.1101/2023.02.16.528790