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Impact of Measurement Imprecision on Genetic Association Studies of Cardiac Function

BACKGROUND: Recent studies have leveraged quantitative traits from imaging to amplify the power of genome-wide association studies (GWAS) to gain further insights into the biology of diseases and traits. However, measurement imprecision is intrinsic to phenotyping and can impact downstream genetic a...

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Detalles Bibliográficos
Autores principales: Vukadinovic, Milos, Renjith, Gauri, Yuan, Victoria, Kwan, Alan, Cheng, Susan C., Li, Debiao, Clarke, Shoa L., Ouyang, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949184/
https://www.ncbi.nlm.nih.gov/pubmed/36824841
http://dx.doi.org/10.1101/2023.02.16.23286058