Cargando…

Remodeling of colon plasma cell repertoire within ulcerative colitis patients

Plasma cells (PCs) constitute a significant fraction of colonic mucosal cells and contribute to inflammatory infiltrates in ulcerative colitis (UC). While gut PCs secrete bacteria-targeting IgA antibodies, their role in UC pathogenesis is unknown. We performed single-cell V(D)J- and RNA-seq on sorte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scheid, Johannes F., Eraslan, Basak, Hudak, Andrew, Brown, Eric M., Sergio, Dallis, Delorey, Toni M., Phillips, Devan, Lefkovith, Ariel, Jess, Alison T., Duck, Lennard W., Elson, Charles O., Vlamakis, Hera, Plichta, Damian R., Deguine, Jacques, Ananthakrishnan, Ashwin N., Graham, Daniel B., Regev, Aviv, Xavier, Ramnik J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949229/ https://www.ncbi.nlm.nih.gov/pubmed/36752797 http://dx.doi.org/10.1084/jem.20220538

Ejemplares similares

Functional analyses and single cell immunoprofiling uncover sex-specific differences in SARS-CoV2 immune memory development
por: Eraslan, Basak, et al.
Publicado: (2022)

Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens
por: Jackson, David R., et al.
Publicado: (2020)

B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
por: Scheid, Johannes F., et al.
Publicado: (2021)

Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level
por: Kenny, Douglas J., et al.
Publicado: (2020)

Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide
por: Henke, Matthew T., et al.
Publicado: (2019)

Capsular polysaccharide correlates with immune response to the human gut microbe Ruminococcus gnavus
por: Henke, Matthew T., et al.
Publicado: (2021)

Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis
por: Plichta, Damian R., et al.
Publicado: (2021)

The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response
por: Lavoie, Sydney, et al.
Publicado: (2019)

Gut bacterial metabolites modulate endoplasmic reticulum stress
por: Ke, Xiaobo, et al.
Publicado: (2021)

Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization
por: Balbontín, Roberto, et al.
Publicado: (2014)

Population structure discovery in meta-analyzed microbial communities and inflammatory bowel disease using MMUPHin
por: Ma, Siyuan, et al.
Publicado: (2022)

From Cell Differentiation to Cell Collectives: Bacillus subtilis Uses Division of Labor to Migrate
por: van Gestel, Jordi, et al.
Publicado: (2015)

Integrated multi-omics analyses reveal homology-directed repair pathway as a unique dependency in near-haploid leukemia
por: Liu-Lupo, Yunpeng, et al.
Publicado: (2023)

Host genetic variation and its microbiome interactions within the Human Microbiome Project
por: Kolde, Raivo, et al.
Publicado: (2018)

Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease
por: Walker, Rebecca L., et al.
Publicado: (2021)

Morphological Heterogeneity and Attachment of Phaeobacter inhibens
por: Segev, Einat, et al.
Publicado: (2015)

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients
por: Hall, Andrew Brantley, et al.
Publicado: (2017)

Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis
por: Martin, Victoria M., et al.
Publicado: (2022)

A missense variant in SLC39A8 confers risk for Crohn’s disease by disrupting manganese homeostasis and intestinal barrier integrity
por: Nakata, Toru, et al.
Publicado: (2020)

Compressed Perturb-seq: highly efficient screens for regulatory circuits using random composite perturbations
por: Yao, Douglas, et al.
Publicado: (2023)

KinD Is a Checkpoint Protein Linking Spore Formation to Extracellular-Matrix Production in Bacillus subtilis Biofilms
por: Aguilar, Claudio, et al.
Publicado: (2010)

Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences
por: Mallick, Himel, et al.
Publicado: (2019)

Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis
por: Chai, Yunrong, et al.
Publicado: (2012)

Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis
por: Chai, Yunrong, et al.
Publicado: (2013)

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome
por: Schirmer, Melanie, et al.
Publicado: (2018)

Lectin-Seq: A method to profile lectin-microbe interactions in native communities
por: McPherson, Robert L., et al.
Publicado: (2023)

A single-cell survey of the small intestinal epithelium
por: Haber, Adam L., et al.
Publicado: (2017)

Longitudinal trajectories of anxiety, depression, and bipolar disorder in inflammatory bowel disease: a population-based cohort study
por: Bisgaard, Tania H., et al.
Publicado: (2023)

An intracellular anion channel critical for pigmentation
por: Bellono, Nicholas W, et al.
Publicado: (2014)

Impact of Diet on Risk of IBD
por: Ananthakrishnan, Ashwin N
Publicado: (2020)

Delivery Mode Affects Stability of Early Infant Gut Microbiota
por: Mitchell, Caroline M., et al.
Publicado: (2020)

Author Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations
por: Stražar, Martin, et al.
Publicado: (2021)

Publisher Correction: Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations
por: Stražar, Martin, et al.
Publicado: (2021)

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations
por: Stražar, Martin, et al.
Publicado: (2021)

Structure-based protein function prediction using graph convolutional networks
por: Gligorijević, Vladimir, et al.
Publicado: (2021)

The evolution of drug resistance in clinical isolates of Candida albicans
por: Ford, Christopher B, et al.
Publicado: (2015)

Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics
por: VanDuijn, Martijn M., et al.
Publicado: (2017)

Mixing and Matching Siderophore Clusters: Structure and Biosynthesis of Serratiochelins from Serratia sp. V4
por: Seyedsayamdost, Mohammad R., et al.
Publicado: (2012)

Vitamin D deficiency is associated with community-acquired clostridium difficile infection: a case–control study
por: Sahay, Tanya, et al.
Publicado: (2014)

The Doctor Will Call You Now! Telemedicine in the Midst of a Pandemic
por: Ananthakrishnan, Ashwin N., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vfftf2crjatn8g5pqdhc2f4gcq