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Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates the axon guidance genes robo2 and slit in Drosophila

Modifications of mRNA, especially methylation of adenosine, have recently drawn much attention. The much rarer modification, 5-hydroxymethylation of cytosine (5hmC), is not well understood and is the subject of this study. Vertebrate Tet proteins are 5-methylcytosine (5mC) hydroxylases enzymes catal...

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Detalles Bibliográficos
Autores principales: Singh, Badri Nath, Tran, Hiep, Kramer, Joseph, Kirishenko, Elmira, Changela, Neha, Wang, Fei, Feng, Yaping, Kumar, Dibyendu, Tu, Min, Lan, Jie, Bizet, Martin, Fuks, François, Steward, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949232/
https://www.ncbi.nlm.nih.gov/pubmed/36824980
http://dx.doi.org/10.21203/rs.3.rs-2511705/v1