Extracellular vesicle-Serpine-1 affects neural progenitor cell mitochondrial functions and synaptic density: modulation by amyloid beta and HIV-1

Brain endothelial extracellular vesicles carrying amyloid beta (EV-Aβ) can be transferred to neural progenitor cells (NPCs) leading to NPC dysfunction. However, the events involved in this EV-mediated Aβ pathology are unclear. EV-proteomics studies identified Serpine-1 (plasminogen activator inhibit...

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Detalles Bibliográficos
Autores principales: András, Ibolya E., Serrano, Nelson, Djuraskovic, Irina, Fattakhov, Nikolai, Sun, Enze, Toborek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949237/
https://www.ncbi.nlm.nih.gov/pubmed/36824983
http://dx.doi.org/10.21203/rs.3.rs-2551245/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949237/
https://www.ncbi.nlm.nih.gov/pubmed/36824983
http://dx.doi.org/10.21203/rs.3.rs-2551245/v1

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