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Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke

Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. Thus, identifying genes that modulate microglial function may reveal novel therapeutic interventions for promoting be...

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Detalles Bibliográficos
Autores principales: Kim, Gab Seok, Harmon, Elisabeth, Gutierrez, Manuel, Stephenson, Jessica, Chauhan, Anjali, Banerjee, Anik, Wise, Zachary, Doan, Andrea, Wu, Ting, Lee, Juneyoung, Jung, Joo Eun, McCullough, Louise, Wythe, Joshua, Marrelli, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949241/
https://www.ncbi.nlm.nih.gov/pubmed/36824976
http://dx.doi.org/10.21203/rs.3.rs-2557290/v1