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Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke
Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. Thus, identifying genes that modulate microglial function may reveal novel therapeutic interventions for promoting be...
Autores principales: | Kim, Gab Seok, Harmon, Elisabeth, Gutierrez, Manuel, Stephenson, Jessica, Chauhan, Anjali, Banerjee, Anik, Wise, Zachary, Doan, Andrea, Wu, Ting, Lee, Juneyoung, Jung, Joo Eun, McCullough, Louise, Wythe, Joshua, Marrelli, Sean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949241/ https://www.ncbi.nlm.nih.gov/pubmed/36824976 http://dx.doi.org/10.21203/rs.3.rs-2557290/v1 |
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