Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo

Gene editing strategies for cystic fibrosis are challenged by the complex barrier properties of airway epithelia. We previously reported that the amphiphilic S10 shuttle peptide non-covalently combined with CRISPR-associated (Cas) ribonucleoprotein (RNP) enabled editing of human and mouse airway epi...

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Detalles Bibliográficos
Autores principales: Kulhankova, Katarina, Traore, Soumba, Cheng, Xue, Benk-Fortin, Hadrien, Hallée, Stéphanie, Harvey, Mario, Roberge, Joannie, Couture, Frédéric, Gross, Thomas, Newby, Gregory, Liu, David, Tarantal, Alice, Guay, David, McCray, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949254/
https://www.ncbi.nlm.nih.gov/pubmed/36824928
http://dx.doi.org/10.21203/rs.3.rs-2540755/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949254/
https://www.ncbi.nlm.nih.gov/pubmed/36824928
http://dx.doi.org/10.21203/rs.3.rs-2540755/v1

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