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Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo
Gene editing strategies for cystic fibrosis are challenged by the complex barrier properties of airway epithelia. We previously reported that the amphiphilic S10 shuttle peptide non-covalently combined with CRISPR-associated (Cas) ribonucleoprotein (RNP) enabled editing of human and mouse airway epi...
Autores principales: | Kulhankova, Katarina, Traore, Soumba, Cheng, Xue, Benk-Fortin, Hadrien, Hallée, Stéphanie, Harvey, Mario, Roberge, Joannie, Couture, Frédéric, Gross, Thomas, Newby, Gregory, Liu, David, Tarantal, Alice, Guay, David, McCray, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949254/ https://www.ncbi.nlm.nih.gov/pubmed/36824928 http://dx.doi.org/10.21203/rs.3.rs-2540755/v1 |
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