Cargando…

Pro-phagocytic function and structural basis of GPR84 signaling

GPR84 is a unique orphan G protein-coupled receptor (GPCR) that can be activated by endogenous medium-chain fatty acids (MCFAs). The signaling of GPR84 is largely pro-inflammatory, which can augment inflammatory response, and GPR84 also functions as a pro-phagocytic receptor to enhance phagocytic ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xuan, Wang, Yujing, Supekar, Shreyas, Cao, Xu, Zhou, Jingkai, Dang, Jessica, Chen, Siqi, Jenkins, Laura, Marsango, Sara, Li, Xiu, Liu, Guibing, Milligan, Graeme, Feng, Mingye, Fan, Hao, Gong, Weimin, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949259/
https://www.ncbi.nlm.nih.gov/pubmed/36824923
http://dx.doi.org/10.21203/rs.3.rs-2535247/v1