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Potential therapeutic targets for sarcopenia identified by Mendelian randomisation

BACKGROUND: Identifying sarcopenia’s causally associated plasma proteins would provide potential therapeutic targets. METHODS: We screened out sarcopenia-related proteins with genome-wide association studies (GWAS) summary data and cis-protein loci genetic instruments. Summary data of sarcopenia wer...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Zhan, Wenli, Zhou, Luoqi, Dong, Minghao, Liu, Liang, Xu, Xiangshang, Cao, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949583/
https://www.ncbi.nlm.nih.gov/pubmed/36821647
http://dx.doi.org/10.1093/ageing/afad024