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Rhodopsin-positive cell production by intravitreal injection of small molecule compounds in mouse models of retinal degeneration

We aimed to verify whether the intravitreal injection of small molecule compounds alone can create photoreceptor cells in mouse models of retinal degeneration. Primary cultured mouse Müller cells were stimulated in vitro with combinations of candidate compounds and the rhodopsin expression was measu...

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Detalles Bibliográficos
Autores principales: Fujii, Yuya, Arima, Mitsuru, Murakami, Yusuke, Sonoda, Koh-Hei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949636/
https://www.ncbi.nlm.nih.gov/pubmed/36821627
http://dx.doi.org/10.1371/journal.pone.0282174