Neutral amino acid transporter SLC38A2 protects renal medulla from hyperosmolarity-induced ferroptosis

Hyperosmolarity of the renal medulla is essential for urine concentration and water homeostasis. However, how renal medullary collecting duct (MCD) cells survive and function under harsh hyperosmotic stress remains unclear. Using RNA-Seq, we identified SLC38A2 as a novel osmoresponsive neutral amino...

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Detalles Bibliográficos
Autores principales: Du, Chunxiu, Xu, Hu, Cao, Cong, Cao, Jiahui, Zhang, Yufei, Zhang, Cong, Qiao, Rongfang, Ming, Wenhua, Li, Yaqing, Ren, Huiwen, Cui, Xiaohui, Luan, Zhilin, Guan, Youfei, Zhang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949798/
https://www.ncbi.nlm.nih.gov/pubmed/36722887
http://dx.doi.org/10.7554/eLife.80647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949798/
https://www.ncbi.nlm.nih.gov/pubmed/36722887
http://dx.doi.org/10.7554/eLife.80647

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