Cargando…

Extended preconditioning on soft matrices directs human mesenchymal stem cell fate via YAP transcriptional activity and chromatin organization

Dynamic extracellular matrix (ECM) mechanics plays a crucial role in tissue development and disease progression through regulation of stem cell behavior, differentiation, and fate determination. Periodontitis is a typical case characterized by decreased ECM stiffness within diseased periodontal tiss...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yufei, Zhang, Xu, Tang, Shaoxin, Xue, Li, Wang, Jing, Zhang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949900/
https://www.ncbi.nlm.nih.gov/pubmed/36845904
http://dx.doi.org/10.1063/5.0124424