Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure

PURPOSE: The purpose of this study was to investigate the role of Lysine specific demethylase 1 (Lsd1) in murine retinal development. LSD1 is a histone demethylase that can demethylate mono- and di-methyl groups on H3K4 and H3K9. Using Chx10-Cre and Rho-iCre75 driver lines, we generated novel transg...

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Detalles Bibliográficos
Autores principales: Ferdous, Salma, Shelton, Debresha A., Getz, Tatiana E., Chrenek, Micah A., L’Hernault, Nancy, Sellers, Jana T., Summers, Vivian R., Iuvone, P. Michael, Boss, Jeremy M., Boatright, Jeffrey H., Nickerson, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950115/
https://www.ncbi.nlm.nih.gov/pubmed/36846208
http://dx.doi.org/10.3389/fncel.2023.1104592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950115/
https://www.ncbi.nlm.nih.gov/pubmed/36846208
http://dx.doi.org/10.3389/fncel.2023.1104592

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