Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway

Cisplatin and other platinum-based anticancer agents are among the most widely used chemotherapy drugs in the treatment of different types of cancer. However, it is common to find patients who respond well to treatment at first but later relapse due to the appearance of resistance to cisplatin. Amon...

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Detalles Bibliográficos
Autores principales: Belmonte-Fernández, Alejandro, Herrero-Ruíz, Joaquín, Galindo-Moreno, María, Limón-Mortés, M. Cristina, Mora-Santos, Mar, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950126/
https://www.ncbi.nlm.nih.gov/pubmed/36477079
http://dx.doi.org/10.1038/s41418-022-01100-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950126/
https://www.ncbi.nlm.nih.gov/pubmed/36477079
http://dx.doi.org/10.1038/s41418-022-01100-1

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