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Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway
Cisplatin and other platinum-based anticancer agents are among the most widely used chemotherapy drugs in the treatment of different types of cancer. However, it is common to find patients who respond well to treatment at first but later relapse due to the appearance of resistance to cisplatin. Amon...
Autores principales: | Belmonte-Fernández, Alejandro, Herrero-Ruíz, Joaquín, Galindo-Moreno, María, Limón-Mortés, M. Cristina, Mora-Santos, Mar, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950126/ https://www.ncbi.nlm.nih.gov/pubmed/36477079 http://dx.doi.org/10.1038/s41418-022-01100-1 |
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