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A first-in-class POLRMT specific inhibitor IMT1 suppresses endometrial carcinoma cell growth

Exploring novel molecularly-targeted therapies for endometrial carcinoma is important. The current study explored the potential anti-endometrial carcinoma activity by a first-in-class POLRMT (RNA polymerase mitochondrial) inhibitor IMT1. In patient-derived primary human endometrial carcinoma cells a...

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Detalles Bibliográficos
Autores principales: Li, Shu-ping, Ou, Li, Zhang, Yan, Shen, Fang-rong, Chen, You-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950144/
https://www.ncbi.nlm.nih.gov/pubmed/36823110
http://dx.doi.org/10.1038/s41419-023-05682-7