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BCL-2 protein family: attractive targets for cancer therapy

Acquired resistance to cell death is a hallmark of cancer. The BCL-2 protein family members play important roles in controlling apoptotic cell death. Abnormal over-expression of pro-survival BCL-2 family members or abnormal reduction of pro-apoptotic BCL-2 family proteins, both resulting in the inhi...

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Detalles Bibliográficos
Autores principales: Kaloni, Deeksha, Diepstraten, Sarah T, Strasser, Andreas, Kelly, Gemma L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950219/
https://www.ncbi.nlm.nih.gov/pubmed/36342579
http://dx.doi.org/10.1007/s10495-022-01780-7