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RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling

Spermatogenesis is an extremely complex process, and any obstruction can cause male infertility. RhoGDIα has been identified as a risk of male sterility. In this study, we generate RhoGDIα knockout mice, and find that the males have severely low fertility. The testes from RhoGDIα(−/−) mice are small...

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Detalles Bibliográficos
Autores principales: Zhu, Haixia, Wen, Zongzhuang, Zhang, Aizhen, Liu, Dongyue, Wang, Hongxiang, Cheng, Yin, Yang, Xing, Xiao, Yu, Li, Jianyuan, Sun, Daqing, Wu, Bin, Gao, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950379/
https://www.ncbi.nlm.nih.gov/pubmed/36823181
http://dx.doi.org/10.1038/s42003-023-04579-7