A cross-tissue transcriptome association study identifies key genes in essential hypertension

Genome-wide association study (GWAS) have identified over 1,000 loci associated with blood pressure. However, these loci only explain 6% of heritability. Transcriptome-wide association studies (TWAS) combine GWAS summary data with expression quantitative trait loci (eQTL) to provide a better approac...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Sihui, Wang, Jie, Liu, Nannan, Li, Ping, Wu, Sha, Qi, Luming, Xia, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950398/
https://www.ncbi.nlm.nih.gov/pubmed/36845374
http://dx.doi.org/10.3389/fgene.2023.1114174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950398/
https://www.ncbi.nlm.nih.gov/pubmed/36845374
http://dx.doi.org/10.3389/fgene.2023.1114174

Ejemplares similares