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A cross-tissue transcriptome association study identifies key genes in essential hypertension

Genome-wide association study (GWAS) have identified over 1,000 loci associated with blood pressure. However, these loci only explain 6% of heritability. Transcriptome-wide association studies (TWAS) combine GWAS summary data with expression quantitative trait loci (eQTL) to provide a better approac...

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Detalles Bibliográficos
Autores principales:	Huang, Sihui, Wang, Jie, Liu, Nannan, Li, Ping, Wu, Sha, Qi, Luming, Xia, Lina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950398/ https://www.ncbi.nlm.nih.gov/pubmed/36845374 http://dx.doi.org/10.3389/fgene.2023.1114174

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