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In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles

Nanoparticle-based drug delivery systems have the potential to revolutionize medicine, but their low vascular permeability and rapid clearance by phagocytic cells have limited their medical impact. Nanoparticles delivered at the in utero stage can overcome these key limitations due to the high rate...

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Detalles Bibliográficos
Autores principales: Gao, Kewa, Li, Jie, Song, Hengyue, Han, Hesong, Wang, Yongheng, Yin, Boyan, Farmer, Diana L., Murthy, Niren, Wang, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950423/
https://www.ncbi.nlm.nih.gov/pubmed/36844366
http://dx.doi.org/10.1016/j.bioactmat.2023.02.011