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In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles
Nanoparticle-based drug delivery systems have the potential to revolutionize medicine, but their low vascular permeability and rapid clearance by phagocytic cells have limited their medical impact. Nanoparticles delivered at the in utero stage can overcome these key limitations due to the high rate...
Autores principales: | Gao, Kewa, Li, Jie, Song, Hengyue, Han, Hesong, Wang, Yongheng, Yin, Boyan, Farmer, Diana L., Murthy, Niren, Wang, Aijun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950423/ https://www.ncbi.nlm.nih.gov/pubmed/36844366 http://dx.doi.org/10.1016/j.bioactmat.2023.02.011 |
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