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A multidimensional ODE-based model of Alzheimer’s disease progression
Data-driven Alzheimer’s disease (AD) progression models are useful for clinical prediction, disease mechanism understanding, and clinical trial design. Most dynamic models were inspired by the amyloid cascade hypothesis and described AD progression as a linear chain of pathological events. However,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950424/ https://www.ncbi.nlm.nih.gov/pubmed/36823416 http://dx.doi.org/10.1038/s41598-023-29383-5 |