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Targeting ubiquitin-specific protease 8 sensitizes anti-programmed death-ligand 1 immunotherapy of pancreatic cancer

Programmed death-1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) help tumor cells evade immune surveillance, and are regarded as important targets of anti-tumor immunotherapy. Post-translational modification of PD-L1 has potential value in immunosuppression. Here, we identified that ubiqui...

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Detalles Bibliográficos
Autores principales: Yang, Hanshen, Zhang, Xiaozhen, Lao, Mengyi, Sun, Kang, He, Lihong, Xu, Jian, Duan, Yi, Chen, Yan, Ying, Honggang, Li, Muchun, Guo, Chengxiang, Lu, Qingsong, Wang, Sicheng, Su, Wei, Liang, Tingbo, Bai, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950432/
https://www.ncbi.nlm.nih.gov/pubmed/36539510
http://dx.doi.org/10.1038/s41418-022-01102-z